There is a small sub dedicated to gaming on OpenBSD:

https://old.reddit.com/r/openbsd_gaming/

Most recent post shows an older version of Minecraft running. And OpenBSD can be a perfectly usable general desktop OS with some configuration.

Vulkan seems to be incomplete. Graphics drivers for Nvidia are a problem due to the project not accepting blobs, not signing NDAs. And today I had a problem installing matplotlib (ninja gave some error). AFAIK, tensorflow and/or python libs are a problem with *nix as well.

On the good side, the system is VERY predictable.

Latency sensitive? I'd guess you'd have some issues, because I've read that OpenBSD doesn't have syscalls to set cpu affinity for userspace threads/processes, which means you're subject to the kernel scheduler and might have tasks move in less than ideal ways.

Not that I have ever enabled graphics or sound on my OpenBSD boxes - but I would say it’s probably not my first, second or third choice of OS for this.

But my recording studio would probably bore you as I just run macOS for both graphics and sound work.