Yes. Many services abstract networking. App Runner, for example, even gives you a public URL with HTTPs. Lambda also can do that nowadays. Most managed services just expose endpoints.
> I'll probably get downvoted, but isn't global addressing + firewalling basically available by creating a VPC with only public subnets, and using security groups as your firewall? (Best practice is public/private subnets with NAT gateways, but it's probably not impossible to rely only on security groups)
I will also disagree with what others are saying. You can keep things simple in AWS if your use case is simple and never care about 99% of what's on the AWS VPC dashboard.
If your use case is complex (you need to connect several internal private apps, expose private things behind a single IP / FQDN, do load balancing, use private DNS, connect with other clouds and on-premises, segregate, monitor and authenticate traffic...) then using physical appliances would likely require more hard work and expertise.
A fun exercise to folks complaining about AWS complexity: go to Fortinet's web site and try to find out which appliances you should use to secure a small company (~ 100 employees, couple of public internet facing services, couple of internal apps), how much it costs and how can you buy it.