I have to run humidification where I am, and that's handled by the hvac which has a humidity control system in it. That has to get serviced yearly, but, other than that it stays between 40-50% without any intervention.

Generally, any HVAC system will dry the air quite a bit, but only when it's running, so if you live in, say, Kentucky, it's likely that if outdoor temp = indoor temp at night, you can have your windows open, and when you close them in the morning, the next day's worth of HVAC usage will take care of any additional humidity without much trouble.

The real downside of that is that you'll have to run your HVAC system harder, because dry air feels cooler than humid air.