I had a Japanese teacher who liked to talk about how surprised she was about the title in English.

She also gave me a little insight into the word 神隠し which, apparently comes from a saying. When children used to go missing, people used to say that "God snatched them away", which is why the first kanji 神 is 'god'.

Her translation of the title was "God snatched sen & chihiro away" which of course isn't a literal translation, but I thought it was interesting