It's used to treat chronic, systemic inflammation and is one of the only "tools in the toolbox" for some very desperate people in long-term pain for years because you can't use things like corticosteroids which are destructive.
There are some cases where it can reduce inflammation well enough and long enough in some people for the body to self-heal where it could not before as the damage was too severe and dysfunctional.
This is a good site for layperson information or use google scholar for actual research
https://ldnresearchtrust.org/what-is-low-dose-naltrexone-ldn
I know a guy who says that drinking noni juice cures all sorts of cancers. With your Youtube wisdom and my friends noni expertise, I'm sure the world will soon be cancer free.