Avoiding GC doesn't equate to "manual memory management." Objective-C uses reference counting, which is only manual in Objective-C for historical reasons, and they're trying to overcome that with ARC. I'm pretty sure most popular scripting languages use reference counting instead of garbage collection. C++ with pervasive use of shared pointers shouldn't be characterized as "manual" either.
Also, as of a few years ago, the only performance-related reason why the JVM wasn't a popular language for desktop GUI apps was startup time. (In the mobile space, it might be true that Java isn't fast enough on current hardware. My experience with Android hasn't been very inspiring, for sure.)
Keep in mind that desktop GUI frameworks take a HUGE amount of time and labor to create, and almost all of the excitement has been in web apps for the last decade. The status quo in GUI frameworks is heavily colored by history. All of the major GUI application frameworks are ancient and reflect the linguistic realities of the year 2000 much more than they reflect current technology.