1. Dwelling on the utter absurdity of the universe appearing from nowhere without the intervention of a power well beyond our means to understand is a good start.

2. Try to move from the dominant paradigm of scientific analysis (nothing wrong with it, in its place!) which breaks things down into smaller things, to a narrative or holistic view of the world. They're both equally valid, and both can be considered fundamental. There are things happening in the world and to you. Those things are all imbued with meaning. Nothing is meaningless. What is the story of your life, what is your mission? If the events of your life were trying to tell you something, what would that be?