You can do all these but the disk quota with systemd. If you don't want to define a unit file, you can use the CLI:

    sudo systemd-nspawn \
        --directory=/ \
        --volatile=yes \
        --bind=/home/tmp:/home/tmp \
        --private-network \
        --port=tcp:80:8000 \
        --property=CPUQuota=5% \
        --property=MemoryMax=1G \
        -- \
        bash -c 'yes > /dev/null'