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Isolation is a big one. The classic study people bring up is the “cocaine rat”.

The rat in isolation was drawn to the bottle with cocaine water. When the rat was in a cage with activites and other rats, lost the preference for the cocaine water.

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Do you have a citation? A search for "cocaine rat study" mostly turned up references to the Rat Park experiment, which used morphine. A later study comparing heroin and cocaine found that social isolation increased overall usage of heroin (apparently because the isolated rats picked up the habit faster) but not cocaine, and that by the fifth week of the study usage rates were similar between isolated and non-isolated groups for both drugs [1].

[1] https://pubmed.ncbi.nlm.nih.gov/2616610/

I would hope that "cocaine rat" is a major motion picture soon to be coming to theaters near you.

Give humans in a room together a vat of cocaine water and that vat will be quickly drained lol

Doing drugs in isolation is a coping mechanism, doing drugs with others is social bonding

So what if you remove the vat of cocaine water by just removing the vat instead of by permanently crippling the other "rats" with 40,000 life-long collateral penalties after a jail where they could easily have been killed inside of?

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