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i don't think anybody really claims python can't be used to build large software

the claim is usually more about how the maintenance costs are just way higher versus a statically typed language

But is that true if the dynamically typed language has type annotations?

it's a spectrum, of course, but imo yes -- i don't want types to be opt-in at compile time, i want them to be mandatory

They truly and tangibly help somewhat but people give them too much credit.