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Something that can handle those kinds of amps and had a simple low-voltage cut off would be amazing (I'm thinking using them for abuse of power tool batteries, which normally don't have a cutoff in them).

There are weird adjustable ones on eBay but they're not terribly reliable and seem to not handle larger amperages.

This would've been so nice when I was rebuilding an RV. I had converted nearly everything to 12V(before Dell & IBM did charger authentication) and ended up with little 12V fused distribution blocks everywhere.

Sweet!

I want the same thing plus current and voltage monitoring and the ability to shutdown certain circuits. I have a design for a wifi (or bt) operated 1000A relay to disconnect the starting and the house batteries.

You may have seen this already but the Redarc RedVision system might be more in line with your use case:

https://www.redarcelectronics.com/us/redvision

Thank you!

Nifty!! Good luck :)