I've tried to use Acme as well and the mouse chords were very difficult to use. I guess it needs an old-school three button mouse (gamer mouses with side buttons didn't help).
My solution to _that_ is to just write text in Acme always and copy/paste it into the destination when I'm done :)
But there aren’t many mice like these. Personally I picked up the N700 and it’s a fine enough mouse but I wouldn’t use it with any other system except some form of Plan 9 with Acme. Not my favorite.
Your preferred settings can be saved to the mouse's onboard memory, so you only have to install the programming crapware on one system.
https://github.com/karahobny/acme2k
https://github.com/aarzilli/yacco
HTH