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Both android and iOS natively let you set a custom DNS server and there are several that include adblocking (or you can host your own). It's not as good as application level blocking but it's quite effective.

I recommend NextDNS as a hosted, paid, custom DNS provider.

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I moved away from NextDNS due to how slowly it picked up DNS changes, it would take hours for changes to propagate - and there wasn't any way to force it to update without manually creating DNS entries. I installed PiHole on one of my servers and Tailscale makes it available on all my devices - I couldn't be happier.

How's the latency with pihole over tailscale? I have a feeling it would make a noticeable difference for me

I haven't had any issues with latency personally.

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