In school, I handled the network for students, we had a /22. I was still afraid to use .0 and .255.
If you choose to use .0, then you have a cosmetic / mental issue ("omg numbering starts at 1, not at 0).
If you choose NOT to use .0 then you potentially save yourself hours of troubleshooting one day, and avoid productivity issues.
Reliability + Productivity > Cosmetic.