Many languages have tried to attach "disposers" to garbage collection events. The more common term in this case is "finalizer". As far as I know, no language has ever had a general-purpose, robust solution that works so well that it can just be used. Many have tried, and they all end up either deprecated, determined by the community to be a footgun, or backed down to some specialized use case (like picking up after file handles that are GC'd but the expected thing is still that normal user code closes them and this is explicitly pitched as an undesirable fallback, not the thing you should do).
For example, if you're using three.js, various WebGL resources need to be manually disposed: https://threejs.org/docs/index.html#manual/en/introduction/H...
Here are common pitfalls: https://auth0.com/blog/four-types-of-leaks-in-your-javascrip...
A more useful definition is memory that remains allocated unintentionally.
If your program continuously allocates memory that it doesn't free and doesn't serve a useful purpose, it doesn't really matter if it's, e.g., being referenced by some cache or just completely unreferenced -- it's still causing the same problem and has the same solution (that is, release the memory when you're done with it -- whether that's by calling "free" or clearing the reference, or whatever your memory management system has)