Cream for skin is same thing but over the course of a day. Plus it’s crazy expensive.
Eventually decide it’s not worth it and start finding out why levels are low and try and fix underlying causes.
TRT forums are kind of fascinating because they're full of people who though (or, sadly, were convinced by TRT clinics) that TRT was going to be amazing, solve all of their problems, and make them feel like 20 year olds again.
Then the realities of getting your hormones from imperfect exogenous sources and dealing with all of the imperfect complications thereof set in. A lot of disappointed stories from people who feel marginally better but thought it was going to cure every struggle in their lives. Unfortunately, a lot of people with depression issues also end up in TRT clinics because hypogonadism is a more palatable diagnosis than mental health issues for many.
https://www.researchgate.net/figure/Multiple-dose-pharmacoki...
While we know all about esters, doctors think “lmao just give a 3 day half life every 14 days bro” which is why people like this end up screwed.
The worst is psych meds. They put people on monthly injections for anti-psychotics despite the fact that they clearly don’t last a month. Those patients then end up going insane for the last week of every month putting everyone at risk. Two week injections would solve it, but no. Monthly.
Medicine as a field just doesn’t seem to realise how much of a difference dosing interval makes. Whereas recreational users know because daily vs weekly is ridiculous obvious through side effects.