Sure thing.
I think, based upon the accounts of others - both what I have read, history, and people who have told me their stories, I think it bridges or removes the brain-to spiritual realm sensors. That is to say, an analogy - like suddenly being able to see infrared light. Something that does exist, but well within another realm of unseen reality, currently undetectable with existing senses. Now, hypothetically, IF there is a spiritual realm, hidden from our natural senses, if those senses were altered in a way, perhaps with natural chemicals found in nature, then suddenly those who were interacting with Angels, Demons, Monsters, Ghosts, etc. are not crazy or mentally ill but simply operating under enhanced or altered states of mind.
Joe/Suzanne describe their trips: https://www.youtube.com/watch?v=Fn_bfhvoX2c
How can two people experience the exact same "grid effect" when on a trip when what they see is entirely in their mind?