I chose the opposite of customization: I decided to train really hard on my standard country-specific 104/105-key keyboard layout. After 20 years I can blindly type every symbol, reach every key, grab the mouse and find my way back, thanks to those 2 notches on the letters 'F' and 'J' to position your index fingers. I bring such a wireless keyboard with me wherever I go - even on vacation - as I cannot work with notebook layouts or Mac keyboards. I'm confident that this keyboard type will be available to buy for a long time.
Not having to take my eyes off the screen prevents a lot of mistakes.