"But what was really notable about this grant proposal was that they proposed to insert cleavage sites, similar to the mystifying furin cleavage site in the SARS-CoV-2 genetic sequence, and to insert those into their coronavirus sequences to see if it would make them more infectious. And to many people, when that was exposed, that DARPA grant — and it only got exposed, I believe, last year — that really looked like a kind of smoking gun, which was that the research that was being proposed in the DARPA grant looked like a kind of directional arrow to a SARS-CoV-2-like virus. So that was quite significant." - https://theintercept.com/2022/05/06/deconstructed-lab-leak-c...

"Farzan was “bothered by the furin site and has a hard time explaining that as an event outside the lab (though, there are possible ways in nature, but highly unlikely).” On the question of whether the virus had a natural origin or came from some sort of accidental lab release, Farrar reported that Farzan was “70:30” or “60:40” in favor of an “accidental-release” explanation and that “Bob” — an apparent reference to Robert Garry — was also surprised by the presence of a furin cleavage site in this virus. Farrar quoted Bob saying: “I just can’t figure out how this gets accomplished in nature. … it’s stunning.” - https://theintercept.com/2023/01/19/covid-origin-nih-emails/