I just moved my Raspberry Pi 4 (8MB) from Ubuntu to Debian 11. I run Ubuntu in several other environments so having one common Linux has been good. But Debian 11 is significantly faster. Same hardware, just noticeably faster.
There are a few anomalies, I suspect mostly from the fact that Gnome is a post install add on. The Gnome network applet doesn't work but the network works fine. The only thing that is problematic on the PI is Firefox - it lags.
I intend to slowly migrate my other systems -Desktop, Digital Ocean to Debian after a bit longer.