My first CPU, the 6502, also used in the Apple II, had approx 4500 transistors!

That isn't really a good example of transistors well spent. You can do 32 bit RISCV or MIPS cpu in the same process node that is 2-6x faster than that 8086 using the same number of transistors.

The human brain has 0 transistors!

It's apples to oranges but here we go:

  M2   134bn 192GB  RAM   800GB/s   3 TFlops?  $9,600

  H100  80bn 188GB VRAM   900GB/s  60 TFlops  $40,000

  A100  54bn  80GB VRAM   600GB/s  20 TFlops  $10,000

  4090  76bn  24GB VRAM  1000GB/s  82 TFlops   $1,400

[1] https://www.nvidia.com/en-us/data-center/h100/

[2] https://en.wikipedia.org/wiki/Ampere_(microarchitecture)#A10...

[3] https://en.wikipedia.org/wiki/List_of_Nvidia_graphics_proces...