Out there food and energy are often scarce. Evolution does care about efficiency in that particular case a lot. True, there are ecosystems with plenty of free food but they are rarity.
This is an example. Epigenetically driven evolution in arabodopsis, which protects certain regions from mutation. In a very limited sense, evolution might be said to "care" about something here, as it is kind of taking direction from the environment, not simply acting on uniformly random mutations. Nothing like this is known in animals or most anywhere else afaik.