Aside from the key well, the integrated palm rest is a big factor of how the keyboard works. The ergodox variants all require to raise your hands to operate, or use a dumb palm rest. But the position of a normal palm rest doesn't work with the shape of these keyboards.
I also don't get why so many try to reach for the small form factor, literally shaving 1-2 cm and loosing a ton of keys and then spend time adding layers later with all the complexity that this entails. This is also something I'm not fond of the advantage 360 -- loosing the fn row (I would likely have upgraded otherwise).
I wasn't aware of the glove 80 - that's a very nice option. Thanks for mentioning this. Just looking at this (without trying), I instinctively prefer the thumb cluster of the kinesis due to the double-length keys: these allow to move your hands vertically and still allow the thumb to hit the key without flexing). Considering space/bk/enter is placed there, this is not a small point.
However, this might just be bias after years of kinesis use.