I suppose that it is possible to do something like this. We've explored the idea of synthesizing a workload that behaves like an application's real workload. The idea was to do offline testing with the synthesized workload to find optimal configurations that can then be applied to the production database. Our results were inconclusive (not enough real workloads to verify). But the idea could be extended for what you are proposing.
But in terms of relational vs graph, my opinions about the matter are public:
https://www.theregister.com/Debates/2023/03/06/great_graph_d...