The question is: is this particular hell worth the result?
There is no generic answer to that of course, it just happens is has been the case for me during those 20 years.
First, you have to get to the industrialization phase. And of course, you have to get there, with the constraint of time, budgets, and talent.
Second, Python does have less benefits for that phase than rust or haskel, but it's not impotent. Industrialization is just hard, no matter the language.
Because we are an industry where a lot of self-taught people get a career, we tend to forget this last point. Creating a serious computing system is engineering, and this includes the project management part, and being rigorous about a lot of thing.
Granted, the rigor needs to be higher with Python once your reach that scale, and at a certain point (which I wish everybody would reach), you may want to ditch it. It's a good problem to have though.
Yet we have to remember not all industrialization attempts are equal. Most are really tame. I'd argue you could replace half the website code base out there with a bunch of bash scripts on a VPS and they would still make money. So even in this context, Python can deliver a lot.