Semaglutide users lost 16% bodyweight overall but only 3.4% of their lean mass.
This is study NCT03548935 if you’d like to look it up, there are other statistics of interest in it as well.
The problem is apparently that studies only use change in weight instead of body composition, so doctors have to be aware of that and get the patient measured themselves to make sure they're actually getting leaner instead of losing weight but getting "more obese".
Misinformation. Many of the studies track total fat, lean body mass, visceral fat, and literally dozens of other secondary outcomes/endpoints. See an example of such results here: https://clinicaltrials.gov/ct2/show/results/NCT03548935
This has already been covered yesterday in sibling comments about the NCT03548935 study and Peter Attia being in general a source of misinformation.
Here are some other semaglutide studies which track lean body mass specifically: https://clinicaltrials.gov/ct2/results?cond=Semaglutide&term...
This can lead to the body to break down muscle tissue to obtain protein for energy which could lead to a loss of lean muscle mass
However, maintaining regular exercise and consuming sufficient protein can help to minimize the impact of lean muscle mass loss