AC3D is a 3D mesh editor that uses Tcl/Tk for the UI
inivis.com
inivis.com
Nonetheless, they have some nice qualities and capabilities. And the fact that they were designed in the 1980s/1990s means that they're relatively compact and efficient (especially compared to something like Electron.) I like Tk (and Tkinter for Python) quite a bit and find that you can build some nice and easy to use interfaces with it.
I also still enjoy the retro idea (which Apple and others seem to have abandoned) that UI elements should be visible and discoverable.
Framework name makes the story interesting.