1. If I can fully physically own some of my authenticators. Aka if Yubikeys or similar hardware tokens are supported, so I don't have to long-term trust any corporation to correctly and securely store my credentials - with Yubikeys the only trust is that hardware is free of vulnerabilities or backdoors.
2. If I'm guaranteed to be not bound to any single specific authenticator. Aka if I'm safe if I lose a Yubikey, assuming that I've prepared ahead of time (also see the next point).
3. If I can enroll an authenticator without having it physically present. Aka if I can sign up with one Yubikey and then tell the website "here is my phone, here's the public key of the Yubikey I keep in a safe, and here's a public key of a keypair I've generated on an airgapped machine, etched onto a titanium plate and buried in a secret stash, accept those for me as my alternative authenticators even though I don't have my private keys present". Aka if I don't have to run around the house (or worse) to just sign up for a website.
4. If I'm guaranteed to be able to use a software authenticator of my own development, shall I want it (despite whatever site owners may think of it). Aka if there are no attestation requirements that force me to use authenticators I don't trust.
If it's "yes" to all four, then I'm in and advertising this to everyone I know about, because this is much better than a password manager. If 1, 2 and 4 are "yes" then I'm probably in with a mix of one HSM and one software authenticator with exportable private keys (so I have a guaranteed way out), but voicing my displeasure wherever I can as the system is inconvenient. If not, then I'm probably sticking with passwords for the time being.