Time to get a Brother.
* Sometimes it "forgets" this setting, unsure the conditions to trigger that, but I imagine the retention sloppiness of this setting versus all the other ones it remembers (admin password, etc) is not an accident.
I have had a Brother MFC-L3750CDW for 3.5 years, and have printed over 5000 pages.
Even though I always use third party toners, I haven't seen that color registration issue.
Just now, I just went to the printer and let it do the 'calibration' and 'registration' steps. Then I printed a test image from the internet. None of the colours are offset.
Oh wait, you meant...