On thing I think is well established about aging is that it's not a single factor disease that you can "cure" by removing a well defined cause. Rather, it's a pervasive accumulation of entropy in various systems from various causes that evolution had no ability to correct, so that slowing aging down and reversing it involves a massive amount of tinkering with the watch.
Lowering the drawbridge and opening the gate lets a lot of things happen/go in, both good and bad.
I've heard that it's oftentimes a trade between two extremes, cancer or...well to be honest I've completely forgotten the second one. Huh.
The definition of "random" implies by default that lack of information or knowledge on the object in question is primarily due to cognitive (and hence measurement) limitations of its users, rather than something being 100% objectively ingrained in reality.
There is definitely "real" randomness, DNA replication errors are truly random because they are caused by quantum molecular effects. You can characterize them statistically and reduce their incidence, for example by controlling the diet or shielding the body from UV, but you can't measure those causes, only observe their effects. At best you could correct them, starting from a known-good-copy, as indeed cell biology already does.
https://www.rapamycin.news/t/rapamycin-clinical-trial-update...