Very interesting. The increase in Coeliac disease will mostly be due to the advent of a useful blood test to detect it. The lack of association between other autoimmune diseases and multiple sclerosis fits with the recent identification of Epstein-Barr virus as a probable causative agent. The reduction in pernicious anaemia could be explained by reductions in the prevalence of Helicobacter pylori (due to effective treatment and improvements in food handling).