New study: 70% of type 2 diabetes cases linked to food choices
scitechdaily.com
scitechdaily.com
Food manufacturers IMO only care about making food cheap, making us crave it, and making it last a long time on the shelf. They aren't concerned about making sure it is healthy, as long as it doesn't immediately kill us.
Another example is artificial sweeteners. Studies have shown that sucralose (Splenda) reduces insulin resistance something like 17%. Is anyone making sure that everyone knows that? Hell no.
Now you can get sugary cereal for breakfast, sandwich bread with HFCS for your lunchtime sammo, and a curry jam packed with palm oil and sugar for dinner. And that doesn't count the cookies or Pepsi you slam in between.
Raw sugar of HFCS -- don't matter none, it's that you're slamming em at each meal, all the time.
High fructose corn syrup is a very American thing. Over 90% of the nutritive sweetener used worldwide is sucrose.
There's plenty of evidence from the other point of view demonstrating that HFCS has rather different behaviour than sucrose. Quickly-found example: https://pubmed.ncbi.nlm.nih.gov/22152650/
That's a fun conspiracy theory and all, but he's clearly not advocating for HFCS consumption. Watch the entire talk, he's obviously not pro-corn industry. Infact he does attack HFCS specifically but not for metabolically different reasons.
He's clearly concerned about people mistaking HFCS as the problem when fructose is the problem, and sugar is half fructose, so you're not avoiding it by replacing your HFCS with sucrose. Metabolically they're basically the same.
[1]https://en.wikipedia.org/wiki/Harvey_Washington_Wiley?useski... [2]https://en.wikipedia.org/wiki/Swill_milk_scandal?useskin=vec...
I eat two or three apples just about every day. As far as food habits go I think it’s one of the best I’ve had.
Good luck. I dealt with GI issues that lead to both physical and psychological misery once (after repeated courses of antibiotics), and my advice is to hang in there — you could find something that works for you, even it takes a while.
Again, not a doctor, not a diagnosis, but it might help give you a name that your doctor could look into.
checked out this, out of curiosity https://www.thermofisher.com/diagnostic-education/hcp/de/de/...
Birch also shares an allergen with cashew nuts and tomatoes, afaik
edit: I saw your other reply, there must be other problems, like constipation (fruits should be digested quite quickly and not too quickly too - diarrhea, it takes time to build the right microbiome), not enough mastication maybe too, and not enough fasting
Fermentation is actually something great (before eating), like naturally fermented onions or peppers (they get soft), or almost all non sugary vegetables, allows to skip cooking which destroys most valuable things in vegetable
And by processed foods, I mean foods that are designed to: - Minimize required mastication and digestion time. - Designed to subvert the satiation and cloying defense mechanisms, that tell our body to stop.
1. Mealsquares.com
I'm old and my eating habits aren't going to change but my children are both really interested in these topics and concerned about developing bad eating habits, even though I think I have given them healthy ones.
that is huge... a half kilo apple?!?!
It was a serious apple and required a plan.
Best evidence right now says to maintain a healthy weight, that eating moderately of meats and fats is fine, that we should eat adequately of plant matter, etc. Limit highly processed foods, or foods comprised of large amounts of highly-processed ingredients. Probably because that tends to equate to large amounts of sugar and/or fat.
If your children are really interested and you think it's not going to lead to an obsession then a continuous glucose monitor can lead to fascinating insights about their individual response to specific foods, combinations thereof, the interaction with exercise, etc. If you really want to explore the rabbit hole there's a community of type 1 diabetic hackers; obviously the etiology and hazards are different but as far as collection and analysis of the data there's a lot of prior art there.
- In lab work, "dry mass" refers to what's left when the water is removed. However, "dried" in food science refers to a product's water activity. Since neither 300g of hydrated or dry mass would seem an excessive amount, specifying "fresh or dried apple" would have been more useful.
- Concentrations and amounts vary per unit and variety, and recommendations vary by the individual. If the overall message is "consume fewer calories, especially calories from these compounds, to lower risks of diabetes and live a longer and healthier life", start with those and list common products that contain them - and that don't.
- A great failure in the US is the erosion of food traditions by "convenience"... and sometimes the interference of laws. People do not generally have the background to interpret the creative vocabulary used on food product labels. Even the FDA has trouble with this[1]. Giving clear examples of meals and recommendations for how to buy and store ingredients is helpful to people who have never consumed anything that was not a manufactured food product.
[1] https://www.fda.gov/food/food-labeling-nutrition
The focus of the cycle of food production is largely economics. I'll leave it at that.
Curious if anyone has had something similar.
We pay a lot more than $150 for all sorts of tech that is far more than 20 years old. But if you could make it for $20 or $30/month, that would be a serious innovation and perhaps you should try to start an advanced medical device company.
It’s a medical device with wireless electronics, a mechanism to insert a sensor filament into your skin as painlessly as possible, and a lot of R&D went into making it. It’s not just a “piece of plastic”
The companies charge overhead to have a doctor write a prescription. You can try to find someone who will sell you one from India or another country, but by the time you pay international shipping you’re not saving much.
Regardless, don’t expect it to be all that informative for your condition. If you’re having episodes of hypoglycemia with symptoms, you don’t need a device to tell you that. CGMs are most useful for conditions without overt symptoms, where you need a device to expose the subtle changes. If you’re having episodes, just log that.
> Hopefully I can get a prescription and get this all covered by insurance.
There is a near zero chance that insurance will cover a CGM for curiosity or for diagnostic purposes. If it’s not indicated for a condition and there aren’t significantly powered studies readily available, it’s not something insurance would be interested in.
I used Levels for about 3 months and I saw the same thing over and over again, it was obvious when I was being good about my eating, it was obvious when I went out for happy hour. I learned a couple things, mix a little fat or protein in if you are consuming carbs to blunt the spike, the alert to "take a walk to blunt the spike" is never long enough unless you go for an hour or more. Another year or two of wearing it wouldn't change any of that.
Unless your PC says for your condition of X we are going to try and get your glucose level to never go past Y and see if it fixes it, a CGM for non diabetic people is something you can timebox to 3-ish months, get the data, and get out for under a $1000 one time investment.
That said, wouldn’t it be better to be doing the opposite of what you’re being told, and cut down on carbs (both simple and complex) to eat more protein and fat which body can use to slow-release blood sugar for a longer duration? (For routine diet I mean - obviously at the onset of an attack you’ll want to consume sugar).
Getting the normal glucose meter was great. The poking of the needle barely causes an effect, and you can get pretty ingrained with numbers. The first couple weeks with the thing I went through tons of tests, before meals, various times after meals, and then if the sugar level was high, meaning over 130 for me, I'd go for a 10 minute walk and could see and feel that the numbers dropped to the low 100s so quickly. At this point I can tell decently well what level my number is.
The glucose monitor with poking stick is really great. Better, faster, cheaper, more trustworthy data than the current continuous monitors out there.
It’s also harder to see how quickly your body responds to light exercise unless you carry your poking stick with you lol.
Maybe i’m missing the bigger picture?
Your example is definitely the thing I wanted both glucose monitors for. The CGM didn't seem that great at the giant spikes. With the GM, I'd test numbers right before eating, then 10 minutes into eating, 20, 30, etc. Sure it involved poking my finger, but those were much more informative. than the 15 minutes CGM time frames and the fact the those numbers weren't close to as correct as the blood GM.
True about the light exercise unless you have the poking stick with you. What I did was have an internal treadmill in my apartment building. Example would be test 20 minutes after food, see and feel a 140 reading from the GM, go down and walk for 10 minutes, come back up add see and feel the drop to 100. Learning the feels has been invaluable, and the CGM wouldn't have gotten me the same quick time information that I could trust compared with real time from the direct source.
Hypoglycemia actually causes a panic attack, so symptoms are the same.
It means that my body is insulin resistant, and when I eat anything that raises my sugar levels, the body starts pumping out more and more insulin till it reaches a point where the sugar levels fall below normal. So the body is hit by bad effects of high sugar, and then with bad effects of low sugar.
In my case the solution was to avoid sugars and refined carbs in breakfast. As Indians our breakfast contains a lot of carbs.
If I have eggs for breakfast, I can pretty much anything the entire day and not feel it. On the other hand if I have pancakes with syrup, I know I am in for an episode of hypoglycaemia.
Also if I have sugar or refined carbs, having a fibre supplement (psyllium husk) with it helps.
Overall adding more salad and protein is what I would recommend if you also have this.
PS: For diagnosis go to an endocrinologist.
One trippy thing to try is to go on a keto diet. When your body is in ketosis, it stops using glucose as an energy source, so you shouldn't get hypoglycemia. It's actually a strange feeling. In my case, my energy level feels much more constant throughout the day.
Like, the keto pizza just isn't the same
For example I walk with a friend in the forest and shortly aware that I don't know where I am will turn into "he'll kill me" freakout... assistance dog would notice if something was off, and he's happily sniffing around and enjoying himself.
I figured this out in my twenties, stopped eating convenience food with sugar (cookies, sweet crackers, instant noodles, breakfast cereals), and instantly felt better.
I eat a high-protein breakfast of multigrain toast, avocado, cottage cheese, red onion and ham.
When you eat decent food with protein and vegetables you won't have cravings any more for sugary rubbish.
I snack on roast nuts (no peanuts), eat slightly more often and, for a pick-me-up in the afternoon, eat a small sandwich/ piece of sushi/ etc.
I am occasional only with desserts, cakes and ice-cream; typically only after dinner. Quality makes a big difference; quality cakes for example are mainly eggs, butter, chocolate and a bit of sugar whereas cheap cakes are sugar sugar sugar, refined flour and artificial flavours. Protein and fat seem to help stabilize the effects of dietary sugar on my blood sugar levels and mood.
My personal experience, YMMV.
The glycemic index (GI) relates to the effect food has on the glucose levels after consumption: high is more severe than low. Vegetables have a low index and sugary foods a high one. Surprisingly white bread and cornflakes also have a high index, and other foods we would not describe as sugary.
Maybe the 'bad food' turns out to have a high index.
Now, I’m in better shape and can eat some carbs, but only in relatively small amounts. If I eat fruit, I’ll usually go for a walk immediately, so I don’t get as much of a spike.
It’s also worth noting that I have PTSD, which is strongly linked with endocrine dysregulation, so maybe that’s some of the underlying cause.
The result of all this is that my glucose is now very steady and I’m not having the drops while I sleep. Of course, no doctor advised me to do any of this. This is all n=1 “nonsense” that “evidence based” medicine would ignore.
It needs to be tasty (enough), it needs to be cheap (at least enough to compete with the crap food that's already an option), and it needs to be an option everywhere.
Clearly, regulation is required to force the market to offer healthy options for consumers.
Skip breakfast and lunch. Have a single meal a day and use the time you saved from skipping the other meals to prepare something nutritious and delicious.
It’s so easy that people have been doing it for thousands of years. Except now it’s even easier because you don’t have to stalk a gazelle or wake up at dawn to weed a garden.
For a snack, have some whey protein.
Then you will have the energy to lift weights 3 times a week, and do cardio (or just long walks) days inbetween.
Personally, I know if I consume too much of the above for several days, weeks, or months prior to a blood test, my A1C will be fucked up and bad. I am quite athletic, trim, and thin.
“Our study suggests poor carbohydrate quality is a leading driver of diet-attributable type 2 diabetes globally, and with important variation by nation and over time,” says senior author Dariush Mozaffarian, Jean Mayer Professor of Nutrition and dean for policy at the Friedman School. “These new findings reveal critical areas for national and global focus to improve nutrition and reduce devastating burdens of diabetes.”
Type 2 diabetes is characterized by the resistance of the body’s cells to insulin. Of the 184 countries included in the Nature Medicine study, all saw an increase in type 2 diabetes cases between 1990 and 2018, representing a growing burden on individuals, families, and healthcare systems.
The research team based their model on information from the Global Dietary Database, along with population demographics from multiple sources, global type 2 diabetes incidence estimates, and data on how food choices impact people living with obesity and type 2 diabetes from multiple published papers.
The analysis revealed that poor diet is causing a larger proportion of total type 2 diabetes incidence in men versus women, in younger versus older adults, and in urban versus rural residents at the global level.
Regionally, Central and Eastern Europe and Central Asia —particularly in Poland and Russia, where diets tend to be rich in red meat, processed meat, and potatoes —had the greatest number of type 2 diabetes cases linked to diet. Incidence was also high in Latin America and the Caribbean, especially in Colombia and Mexico, which was credited to high consumption of sugary drinks, processed meat, and low intake of whole grains."
Overall meat consumption (per capita per year) in the US has increased continuously and quite significantly from around 90kg in 1960 to around 120kg in 2000 and stable since then.
https://www.theguardian.com/environment/datablog/2009/sep/02...
This is an unwinnable conflict between population medicine and policy and individual choice.
https://www.cnbc.com/2014/04/09/shrinkflation-the-consumer-g...
Impressive memory!
Compared to 50 years ago, portions are larger and, based on little more than my personal impression, stuff has gotten softer and easier to eat.
Larger packages tend to be have shrunk some, but like there's "shareable" M&Ms or whatever by the register, in a much bigger package than decades ago.
The person I was replying to was talking about supermarket sold mass produced confections, and my response was valid, not based on personal experience and can be easily verified. For most of those things shrinkflation is the predominant force. Ice cream packaging sizes and prepackaged cookies haven’t gotten larger. And if anybody is surprised that these products are loaded with refined sugar (then as now) that’s on the public education system. The fats used have may have changed.
Restaurant portion sizes and content have increased but that’s a different problem. Same as dispensed soft drinks.
> gotten softer and easier to eat.
What does this even mean?
Hostess foods famously went out of business a few years ago. When I think “soft” and calorie dense I can’t imagine any time more representative than the 50s and 60s.
>What does this even mean?
I believe the implication is that packaged food is even more processed than before (less fibre, more multi-syllabic ingredients). The benefit is that our bodies can extract more calories from food (ground beef provides more calories than similar amount of steak). But the increase in type-2 diabetes suggests lack of calories is not a problem for these people.
A 2L bottle of Coke contains 220g of sugar. So half a bottle is less than 1.5 ice creams.
So Coke is indeed half the volumetric sugar content of ice cream. However, I think I probably could fairly handily eat half a Coke-can's worth of ice cream! Half a 2L-bottle's worth of ice cream (1L) would not end well, whereas 2L of Coke is a lot but definitely possible.
[1] Had never realised US cans were slightly larger than what we have (330ml).
Processed meats contain a LOT of salt. Salt doesn't cause diabetes, but it does cause water retention and high blood pressure, so is bad for people with diabetes.
As for sugar, they are on the list of foods they examined. What they found is that we're eating more French fries, so that turns out to be a bigger factor in practice.
Why is salt / bad influence for people with diabetes relevant in this context? Weren’t we interested in meat in relation to the rising global incidence of diabetes? Cottage cheese, shrimp, canned tuna and more also are high in sodium.
Worse, when you aim for that market customers start to want local, organic, grass fed, etc which drastically increases ingredient costs.
So the question is why it's hard to get even moderately low amounts of sugar, say <20% of calories from added sugar.
https://en.m.wikipedia.org/wiki/Renin%E2%80%93angiotensin_sy...
I think the salt consumption is a bit of a red herring and it's better to fix the metabolic syndrome.
This study seems to be the best we have. It’s observational and involved self reporting of diets.
https://journals.plos.org/plosmedicine/article?id=10.1371/jo...
It’s complicated too because nitrites found in fresh vegetables are strongly correlated with health improvements. This could mean that nitrites aren’t the problem, nitrites in the presence of animal proteins is the problem, or in the presence of fat, salt, etc. It doesn’t appear very clear to me.
Any study like this needs to have an explanation for the recentness of obesity and diabetes epidemics.
Consumption of both of those dropped right as the obesity epidemic picked up.
Nicotine is a known appetite suppressant. Alcoholics are known to have terrifically clean arteries (at the cost of liver disease).
This is the video I got it from. I'm in no way an expert on this topic so take it with a bit of salt
The kidneys turn salt into fructose as far as I know. When u're diabetic and you consume salt it's much better to have it in liquid form. I don't think the reasons are known, but it doesn't raise the serum sodium as much.
Huh, how is NaCl turned into C12H22O11. That'd need like a nuclear rection or alchemism.
Dr. Johnson doesn't mention what organ in the body performs the conversion, but he does mention that high serum sodium activates an enzyme which converts glucose to fructose.
Fructose, in high amounts, causes high uric acid, leading to inflammation, insulin resistance, and causes the body to switch from fat-burning to fat storage (bears and migrating birds will increase their fructose consumption before hibernating/migrating).
According to Dr. Johnson, if you eat some food and feel thirsty, that indicates that your body has already started converting glucose to fructose internally. Drinking enough liquid to keep the serum sodium from increasing will prevent this conversion.
from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833672/ (Dr. Johnson is a co-authour of this article) "... activation of aldose reductase in the liver with conversion of glucose to fructose"
Then I found this article, https://www.hindawi.com/journals/ijn/2011/392708/, which states that "The increase in dietary fructose intake stimulates salt absorption in the small intestine and kidney proximal tubule through coordinated activation of PAT1, NHE3, and Glut5. We propose that reducing dietary intake of fructose and salt, as well as maneuvers aimed at inhibiting fructose absorption in the intestine and kidney tubules, could have profound beneficial effect on controlling blood pressure in patients with metabolic syndrome."
Now however, once you get fat and specially fat over the stomach then even high quality carbohydrates can cause high blood sugar which is the definition of diabetes.. so what happens is that low quality carbs plus processed meat leads to being overweight and having a fat stomach, which causes insulin resistance and decreased output from the pancreas.. once you get in this condition however adding whole grains does not help at that point, in fact it adds to your high blood sugar and in fact eating high quality grains at that point, once you have a fat stomach, leads to high blood sugar which is the definition of diabetes
... In other words, once you have fat over the stomach in great quantities, if you eat whole grains, fruits and beans and so forth at that point, that will cause diabetes, diabetes being high blood sugar.. you want to eat the high quality carbs, fruit, and beans before you get fat.. if you eat it after you get fat you will develop diabetes because high quality carbs, fruit, beans etc will give you high blood sugar if you have fat over the stomach
Switched to a keto two months ago and everything has improved. Blood sugar always 90 or less, cholesterol 180, LDL down about 30%.
The journal article breaks it down semi geographically, and call Western Europe and North America "high income countries." Probably a better term than "Western countries," but looks out of place between "Central/Eastern Europe and Central Asia" and "Latin America and the Caribbean."
TBH, they should probably break down East Asia into China, the rest of East Asia, and SEA. That's a huge lump of very wildly varying peoples.
I’ve seen this assertion made universally, but never any explanation of its scientific root.
i am not overweight but i am fat, if that makes sense. Lacking muscle makes you prone to low insulin sensitivity and t2d.
I think this is a source of confusion because people develop it even though they became overweight on relatively healthy food. Or, at the very least, what they consider to be healthy food.
As for this study it seems to indicate to me that certain foods are much easier to get obese with, so they’re linked to the disease.
When you consider carbohydrate quality, a major difference between high and low quality sources is that the higher quality ones are harder to eat more of. That by default is a great protection from obesity. Foods which are harder to eat are almost always better for us if we struggle with portioning.
Take raw carrots for example. You would struggle to become obese by eating raw carrots. On the other hand, you can casually drink like 4 carrots worth of calories in a few minutes via soda. And not feel full at all.
---snip---
Study design
A comparative risk assessment model55 estimated the numbers, proportions and uncertainty of global T2D cases attributable to suboptimal intake of key dietary factors (Extended Data Fig. 1). Comparative risk assessment does not use ecologic correlations to estimate risk but incorporates independently derived inputs and parameters on demographics, risk factors, their etiologic effects and disease incidence to model attributable burdens55. For this investigation, we leveraged input data and corresponding uncertainty in 184 countries on (1) population dietary intake distributions based on individual-level survey data from the GDD (http://www.globaldietarydatabase.org/)56; (2) population overweight (BMI ≥ 25 kg m−2) and underweight (BMI < 18.5 kg m−2) distributions from the NCD-RisC57; (3) total T2D-incidence distributions from the Global Burden of Disease study58,59; (4) linear, BMI-stratified effects of dietary factors on weight gain or loss60; age-adjusted direct etiologic effects of these factors on T2D, adjusted for BMI, and of weight gain on T2D from previous meta-analyses and pooled analyses of prospective cohorts23,61,62; (5) optimal dietary intake levels from previous analyses12; and (6) population demographic data from the United Nations Population Division63,64 and the Baro and Lee 2013 dataset on educational attainment65 (Supplementary Table 6).
https://www.nature.com/articles/s41591-023-02278-8 ---snip---
> stress
> body composition ( muscle is more sensitive to glucose/insulin).
> meal and time of day
> activity post meal ( chilling vs walking ect)
> sleep
When waking up, body goes overdrive into making glucose on its own.
Eating breakfast at all seems to me like a bad idea. You want to keep the fast going for as long as possible, not break it.
:surprised pikachu:
A study by the Friedman School of Nutrition Science and Policy at Tufts University found a correlation between poor diet and 14 million cases of type 2 diabetes worldwide in 2018. Insufficient intake of whole grains, excess refined rice and wheat, and overconsumption of processed meat were identified as significant dietary factors. The research revealed that poor diet has a larger impact on men, younger adults, and urban residents. Central and Eastern Europe, Central Asia, Latin America, and the Caribbean saw the highest number of cases linked to diet. The study suggests that addressing dietary issues can help tackle the global type 2 diabetes epidemic.