Wrt SZ, not only is it very badly understood but a lot of the symptoms can be attributed to biochemical disorders and that does not necessarily imply a genetic predisposition at all.
Caffeine can induce psychosis, so can THC. For instance, caffeine is an adenosine antagonist, which itself is a dopamine antagonist.
So from a DSM pov, a lot many people can be diagnosed SZ when in fact, the amplitude of the disorder is caused by repeated psychoactive substance abuse.
Even owning a cat (parasites) is thought to be a possible cause for schizophrenia.
Then again, who knows what lies in people heads too? Perhaps that the thoughts they hear are real and some people just can't process it properly which drive them to do strange things. We discount people's experience but there are so little ways to non-intrusively explore people's internal state. A true scientist wouldn't discount that possibility too.