Make sure that someone doesn't tamper with your device. No, it's not infallible. Yes, it's better than nothing.
However, let's say that the said industrial equipment is stored in a security box, with tamper-resistant screws, and you are on camera. It's a lot harder to tamper with then, compared to just plugging in a flash drive and rebooting the Pi into USB boot; at least in theory. Ditto for helping to prevent persistent remote attacks.
It's not a powerful device for hosting databases, it's not really used for storage, only for small things like a Kodi server and even that lags.