I've also got Sarcoidosis, some pulmonary involvement, but certainly not debilitating (as long as I remain on medication anyway). However, every time I get prescribed antibiotics for something unrelated, damn I feel so much better for a few weeks after taking them!

A few months back I had an infection that required fairly high dose antibiotics and my Sarcoidosis has been noticeably better since, despite a significant increase in other things that usually cause flare-ups e.g. stress and lack of sleep. I am still on Hydroxychloroquine, but in the past I required Methotrexate (which was horrid).

There's been a heap of studies regarding Mycobacterium and Sarcoidosis. Doesn't seem to be the cause for everyone. As another poster pointed out — Sarcoidosis, Rheumatoid Arthritis; these are basically catch all names for conditions of unknown cause that exhibit similar symptoms. That said I'm pretty optimistic about all this research into bacterial involvement.