https://www.michaeljfox.org/news/thiamine-vitamin-b1-and-par...
The Michael J Fox foundation is more muted and says evidence is still missing. There have only been 2 trials and both were missing a placebo control group.
The Michael J Fox foundation is more muted and says evidence is still missing. There have only been 2 trials and both were missing a placebo control group.
Only if a trial shows extraordinary consistent benefit without drawbacks would they stop it because the placebo group is harmed for lack of access to the treatment.
But the thing that stopped me generalising this was seeing second-hand that trialing a new treatment can be extraordinarily dangerous (and/or fatal).
Imagine being in the experiment group and the untested treatment being a catastrophic failure.
What are the statistics on that?
But I get it. My partner has an untreatable condition (like EDS, but without the genetic markers); they'd jump on any kind of hope, even experimental at this point.
e.g. HAART for HIV/AIDS.