The Colgate I use in the morning has 0.25% sodium fluoride for comparison, so the prescription toothpaste is 4x stronger.
There are some threads on /r/dentistry/ suggesting that SnF2 can cause irritation.
Whatever compound, the benefit of fluoride toothpaste is increased by not washing it away with a mouth rinse after brushing.
[1] https://dentalhealthessentials.com/fluoridex-sensitivity-rel...