Who's designing and running the simulation, on what infrastructure?
There are information theoretic reasons to suspect the human mind can't parse itself in sufficient detail to write that program, but even without these I feel the rhetorical framing "why should it be possible?" makes more sense than "why shouldn't it". At least with "why shouldn't my dog be capable of understanding this HN exchange?" we've got evidence that mammals can learn that in our favour, and the step change between understanding "walkies" and thought experiments about hypothetical brain emulations is probably smaller than that between spotting which brain excites the EEG scanner more and atomic-level brain emulation.
I'm not discussing whether we, humans can create such a simulation. It is a thought experiment of what we think such a simulated mind would be like and whether it would have intelligence/self-awareness/consciousness/experience qualia/etc.
The topic is whether there is anything fundamentally important about the human wetware which couldn't be substituted by a computer.
Asking "why should it be possible" is very reasonable - but you gotta ask it. My take on it is simple; the interactions between things can be reliably predicted - if not exactly then with a model whose outputs are indistinguishable from reality.
I don't think there are any logical reasons why a different set of atoms cannot be an equivalent mind with identical conscious experience (my mind constituted different atoms yesterday, yet perceives continuity!) though I'm unconvinced of the existence of an entity capable of engineering it (and agnostic on what permutations of atoms are and aren't capable of representing brain state). But that's a very different question to "is it possible for humans to create equivalent consciousness by writing high level code which symbolically represents the molecular behaviour we think is pertinent to thought as electrical signals as a binary code state machine" which is often implied by such a question, the answer to which I think is a fairly confident no. It's commonly suggested that scepticism about the ability of the human mind to be replicated in silicon suggests "something special" about it; when rephrased as a question about actually building it it becomes more of a question about whether there's "something special" about our theories of computation and i/o pattern matching that transcends fundamentally different chemistry, as well as the mother of all engineering problems.
Entirely? We're meat machines.
>Would a computer have intuition? Fight or flight responses?
If your grandmother had wheels would she be a bicycle?