Maybe it's just me, but: love, romantic sexual relationships, and some indescribable things between make life worth living. That's the good shit.
Life is so goddamn short: spend it with interesting, cool, reliable people.
And fuck around while you can because there will be a time when you can't.
You don't have to be clever, smooth, a genius, or perfect.. just treat others as human and be real. An interest in someone other than oneself. If that someone else doesn't reciprocate, move on. With age and practice, it gets as easy and natural as walking.
Regret at the end of life for a path not traveled is a living hell that cannot be undone. The goal in life should be to die happy having done everything and having dented the universe a bit.