Like many have said, the JS framework ecosystem (ok, while kind of a meme much of the time) is a total juggernaut.
I wouldn't mind seeing some kind of.. unholy combination of SSR for JS frameworks with a Rust (or even other language) backend if it was feasible.
JS is still a lot more mature and ergonomic for front-end. Rust is kind of a chore for this kind of work currently. It works, but wasn't designed for it and it feels a bit clumsy. On the flip side, Rust is a safe and super fast server language (Go a great choice as well, or others too).
I suppose I'd like to see some kind of framework that makes it easier to pair the two, instead of insisting that a single language isomorphic approach is best.
This might not be practical - I feel like routing might end up being a nightmare. I'm more just saying it seems harder to pair peanut butter with jelly than it should be and someone smarter than me could probably figure it out :). I'm naively guessing that as long as you had a JS interpreter on the server side, it could be made to work (no problem in Rust for either Node or Deno since embedding those is possible).
We've got thing like Next, SvelteKit, and Fresh. We've also got things like LiveView - there may be a further middleground between the two.