One of the more off the wall sci-fi ideas I saw was a pulp sci-fi novel that had dog brains being used for self driving cars.
The idea stuck with me that maybe sometimes we should give up on optimizing nature and just go along with nature.
Of course neural networks are very much inspired by nature, but since Rosenblatt's time, science has learned that brains are even more complex than previously imagined (and no one ever though brains were simple!)