Any time I see a customer using an ssh or apache version from ten years ago (different from the kernel, but the kernel doesn't give you version disclosure), the list of bugs is all like "if they use RewriteRule and the second URI parameter is echoed unfiltered into a Location header by the application code and it's on Windows then you can do something actually interesting. The standard services' standard feature set is annoyingly boring when outdated ... most of the time.
Predictable sequence numbers would be my first worry, but with TLS and SSH being the main protocols of relevance, it doesn't really matter if you can send off-path traffic into a TCP connection.
https://www.cvedetails.com/vulnerability-list.php?vendor_id=...
All the above seem to be in other Apache products. I think the fact that Apache doesn't run as root helps to mitigate these risks. Having said that, I have had a server compromised (about 20 years ago), through apache, suexec and a vulnerable cgi script, so I think it's best to be paranoid about security. I don't even see suexec on my current ubuntu 20.04 server (I used to just delete it).
Originally it was 2.2