Regarding battery drain in suspend, even if that specific issue gets fixed, the downside of user replaceable memory is that it is not low-power. In suspend, this means a battery life counted in days instead of weeks with regular LPDDR.
The x220 it replaced had a smaller battery and two ddr3 sticks instead of a single ddr4. It still lasted longer than the framework laptop when comparing suspend times, even with deep sleep enabled.