There was a time when people threw around "only works in Chrome" like they did with IE6, but for me it seems it has improved somewhat now.
All the "websites that should be a program" (Netflix, Hulu, Slack, Amazon Video) now run great in FF, without my computer overheating. (though some of them might be on the chopping block if they don't quit blocking me from seeing HD content)
I hear Apple does some special magic in MacOS so that on that platform Safari actually works (compared to the ~real~ non-Apple world, where Safari is slow as heck and why would anyone ever touch that with a 10ft pole.)
It also runs on iOS, even with extension support!
But that wasn't a deal breaker because I got to discover NoScript (still stuck on mv2 but I like the approach vastly better than original uBlock's implementation).
Just waiting to see how this functionality will be handled in mv2 sunset since Noscript has no plans to migrate atm and uBlock lite should be "guttered" for the foreseeable future.