Do you think that the Sackler family has had a positive impact on overdoses in the US?
That said, there will always be demand and that demand would be better served if not criminalized. These drugs should be made available for legal purchase but we need to find ways to incentivize minimizing the sale and consumption of such.
I fail to see the difference between letting an adult drink themselves to death vs doping themselves into oblivion. The former is both legal and acceptable whereas the latter is not; but they're effectively the same.
It's better to use prescription drugs than mystery substance available on the streets. At least you know what you are taking.