Maximize the distance of these singular roads, and build out your road system like a computer-science definition of a tree. Its not very realistic, but it solves more or less all the issues of Cities Skylines. (Or perhaps it is realistic, and matches the behavior of neighborhood planners in the real world).
In contrast, OpenTTD encourages hub/spoke model and recycling of centers. I think its sizes are off but the overall gameplay loop is correct here.
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OpenTTD's "traffic" is pretty dumb, but its infinite. As long as you've got high station ratings, the station will expand and traffic will increase. It doesn't matter what design you have, the traffic increases until you can no longer support it.
So OpenTTD is somewhat self balancing. The stronger a player you are, the more traffic you generate. The weaker a player you are, the less traffic you generate.