Jack Daniels isn’t meth. It is a complex and specific flavor profile that is enormously successful commercially. This profile was not arrived at via chemistry and biology, and it’s currently infeasible to apply chemistry and biology in a lab to replicate this flavor profile. The same is true of the overwhelming majority of other spirits, too. The only method we have to find your way to these extremely precise locations in high-dimensional flavorspace is to religiously follow the ritual that gets us there. On the road to mass production, spirit distillers have run across many pitfalls that look innocuous, minor changes that seem like they couldn’t possibly affect the outcome but nevertheless do. That’s what I mean by trying to crystallize luck. (Yes, chemistry and biology are the fields of science that _would_ describe this process…)