that's cute, what is your "full-size"? I don't have 2 days to run a test, and I'm pretty sure every single compliance requirements we are following would get obliterated the second someone hears about us doing that
Although, cannot agree with the former part. If your tests are running 2 days on a full size clone, and it's an OLTP case, what about users, do they suffer from long query duration too? It sounds like it's time to optimize queries and/or redesign test sets (or both).
If it's bad in testing, it will be bad in prod. That's the idea of testing.
Example: how do you check schema changes?