Not in the US (because of the flammability), unless something's changed very recently.
American homes have plenty of propane/natgas appliances anyway, so what difference does one more make?
But it's connected to what you might consider a tank of nearly infinite volume. It's flow rate limited, but it's fast enough to get an entire house to explosion concentration in much less than a day. Perhaps only an hour.
Point is that we humans manage to figure out how to harness things that might be dangerous when they're useful. And hydrocarbon refrigerants can be very useful so we might figure out how to deal with the relatively small danger they pose.
I don't know when it changed but R-290 (propane) is allowed up to 13oz. My ice maker uses it. I believe it must also be sealed without service ports both to prevent leaks and prevent anyone from connecting normal A/C service equipment to the system. Service requires emptying the system then brazing service ports onto the fill pipes (which are left much longer than normal for this purpose).