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I had some issues like this but only manifested when I was on work trips which lasted weeks to months. I can tough out several days of sleeping in a hotel but the longer the stay the more I react to whatever is common to hotel rooms and the problems breathing / and sleep apnea gradually push me around the bend.

Returning home cures me after a recovery period.

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I wonder, do the hotels you stay at differentiate the smoking and non-smoking rooms?

Where I live does, I once accidentally booked a smoking room and I could not sleep at all. It felt like I was burning my esophagus.

I suspect smokers just don't feel how inflamed their airways are anymore, otherwise I have no idea how anyone could live like that.

You do get used to it. It's not till you quit that you realize how poorly you were breathing before you did.

I'm not a smoker, but nicotine does have an anti-inflammatory effect. Maybe it balances out if you're the one smoking?

Maybe the air-conditioning is drying out your sinus?

Very likely!

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